Increased uptake of 5-hydroxytryptamine by platelets of patients on lithium [proceedings]
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چکیده
منابع مشابه
Specificity of 5-hydroxytryptamine uptake by snail nervous tissue [proceedings].
NEVILLE N. OSBORNE, H. U. SCHRODER and VOLKER NEUHOFF Max-Pianck-Institut fur experimentelle Medizin, Forschungsstelle Neurochemie, 3400 Gottingen, Federal Republic of Germany 5-Hydroxytryptamine is thought to be a transmitter substance and it is generally accepted that in vertebrates it is inactivated at the post-synaptic membrane through a specific transport mechanism back into the pre-synapt...
متن کاملUptake of dopamine and 5-hydroxytryptamine by platelets of patients with Parkinsonism.
The uptake of tritiated dopamine and 5-hydroxytryptamine by platelets from 11 patients with Parkinsonism who were not receiving any medication, and from 11 control subjects matched for sex and for age within a decade was compared. No significant differences were found in the uptake of either amine. Our findings, therefore, provide no support for the belief that there is a generalised defect of ...
متن کاملEffects Uptake of Concanavalin a on 5-hydroxytryptamine by Rabbit Blood Platelets and on Their Ultrastructure
1 Effects of concanavalin A (Con A) and other lectins on 5-hydroxytryptamine (5-HT) uptake by rabbit blood platelets and on their ultrastructure were studied. 2 Uptake of [3H]-5-HT by platelets was decreased by application of Con A, E-PHA (lectin from Phaseoltis vulgaris) and lentil-PHA (lectin from Lens culinaris), but not by wheat germ agglutinin (WGA). Con A induced specific changes in the u...
متن کاملFactors affecting the uptake of 5-hydroxytryptamine by human platelets in an inorganic medium.
Since the original observations on the presence of 5-hydroxytryptamine (serotonin) in blood platelets there have been many reports on the ability of these blood elements to take up this amine (l-10). The early studies of Zucker and Borelli (3), Humphrey and Toh (1) and Hardistey and Stacey (2) clearly showed that the uptake of 5-hydroxytryptamine by platelets resulted in greater concentrations ...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1979
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1979.tb00975.x